Mouse Monoclonal Antibody to PMAIP1
货号：
31771
别名：
APR; NOXA
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13794
规格：
目录价
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Description |
|---|
The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
References |
|---|
| 1.Oncotarget. 2014 Nov 30;5(22):11237-51. 2.Cell Death Dis. 2014 Jan 23;5:e1013. |
Specification |
|
|---|---|
| Aliases | APR; NOXA |
| Entrez GeneID | 5366 |
| Swissprot | Q13794 |
| clone | 1A2D3 |
| WB Predicted band size | 6kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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