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Mouse Monoclonal Antibody to CD334
货号: 31754
别名: FGFR4; TKF; JTK2
应用: WB,FCM
反应种属: Human, Monkey
抗体类型: Primary antibody
Swissprot: P22455
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Description

The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]

References

1.Mol Carcinog. 2018 Aug;57(8):988-996.
2.Oncotarget. 2016 Oct 25;7(43):69976-69990.

Specification

Aliases FGFR4; TKF; JTK2
Entrez GeneID 2264
Swissprot P22455
clone 8A1G2
WB Predicted band size 88kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Monkey
Immunogen Purified recombinant fragment of human CD334 (AA: extra 22-369) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
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