Rabbit Polyclonal Antibody to PDK1(Ab-241)
货号：
P41242
别名：
PDPK1, PkB kinase, Protein kinase B kinase, hPDK1, kinase PDK1
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O15530
规格：
目录价
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Description |
|---|
Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development |
References |
|---|
| Scheid MP,et al. (2005)Mol Cell Biol; 25(6): 2347-63Chen H, et al. (2001) Biochemistry; 40(39): 11851-9Sato S,et al. (2002) J Biol Chem; 277(42): 39360-7Lim MA, et al.(2003)Proc Natl Acad Sci U S A; 100(24): 14006-11Beausoleil SA, et al. (2004)Proc Natl Acad Sci U S A; 101(33): 12130-5 |
Specification |
|
|---|---|
| Aliases | PDPK1, PkB kinase, Protein kinase B kinase, hPDK1, kinase PDK1 |
| Entrez GeneID | 5170; |
| Swissprot | O15530 |
| WB Predicted band size | 63kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.239~243 (A-N-S-F-V) derived from Human PDK1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from MCF, 293 and PC12 cells using PDK1(Ab-241) Antibody P41242.
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Immunofluorescence staining of methanol-fixed MCF7 cells using PDK1(Ab-241) Antibody P41242.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PDK1(Ab-241) Antibody P41242(left) or the same antibody preincubated with blocking peptide(right).
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