产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Mouse Monoclonal Antibody to p7S6 Kinase (Phospho-Ser 411)
货号: P41234
别名: 70 kDa ribosomal protein S6 kinase 2 antibody</br> EC 2.7.11.1 antibody</br> KS6B2_HUMAN antibody</br> p70 beta antibody</br> p70 ribosomal S6 kinase beta antibody</br> p70 S6 kinase beta antibody</br> p70 S6K-beta antibody</br> p70 S6KB antibody</br> p70
应用: WB,IP,IHC,IF
反应种属: Human, Mouse, Rat
抗体类型: Primary antibody
Swissprot: Q9UBS0
规格:
目录价
在线咨询

Description

In studies to elucidate key regulatory pathways in signal transduction, several protein serine/threonine (Ser/Thr) kinases have been identified. Included among such kinases are two distinct families of 40S ribosomal protein S6 Ser/Thr kinases present in somatic animal cells, designated p70 S6 kinase and p90 Rsk kinase. p90 Rsk kinase is maximally activated within minutes of addition of growth factors or phorbol ester to cultured cells followed by activation of p70 S6 kinase. Both enzymes are regulated by serine/threonine phosphorylation, suggesting that specific kinases may exist upstream in the signaling pathway that regulate these kinases. In fact, evidence suggests that one such family of activating enzymes includes the members of the ERK MAP kinase family. The ERK MAP kinases are, in turn, regulated by phosphorylation at threonine and tyrosine residues by a protein kinase designated MEK.

Specification

Aliases 70 kDa ribosomal protein S6 kinase 2 antibody
EC 2.7.11.1 antibody
KS6B2_HUMAN antibody
p70 beta antibody
p70 ribosomal S6 kinase beta antibody
p70 S6 kinase beta antibody
p70 S6K-beta antibody
p70 S6KB antibody
p70 S6Kbeta antibody
p70(S6K) beta antibody
p70-beta antibody
p70-S6K 2 antibody
P70S6K2 antibody
p70S6Kb antibody
Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody
Ribosomal protein S6 kinase beta 2 antibody
Ribosomal protein S6 kinase beta-2 antibody
Rps6kb2 antibody
S6 kinase related kinase antibody
S6 kinase-related kinase antibody
S6K beta 2 antibody
S6K beta antibody
S6K-beta antibody
S6K-beta-2 antibody
S6K2 antibody
Serine/threonine protein kinase 14 beta antibody
Serine/threonine-protein kinase 14B antibody
SRK antibody
STK14B antibody
Entrez GeneID 6199;
Swissprot Q9UBS0
WB Predicted band size 70kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen A sequence containing Ser 411 phosphorylated p70 S6 kinase α isoform 2 of human origin.
Formulation Purified antibody in TBS with 0.05% sodium azide,1%BSA and 50% glycerol.

Application

WB 1/1000-1/1000
IP IP1-2 μg per100-500 μg of total protein(1 ml of cell lysate)
IHC 1/50-1/500
IF 1/100-1/500
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852