Rabbit Polyclonal Antibody to NFkB-p100(Ab-866)
货号:
P41251
别名:
DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2
应用:
WB,IHC,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q00653
规格:
目录价
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Description |
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NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. |
References |
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Qu Z, et al. (2004) J Biol Chem. 279(43): 44563-44572. Xiao G, et al. (2001) Mol Cell. 7(2): 401-409. Baeuerle P A, et al. (1994) Annu Rev Immunol. 12:141-179. Baeuerle P A, et al. (1996) Cell 87:13-20. Haskill S, et al. (1991) Cell 65:1281-1289. |
Specification |
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Aliases | DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10; Lyt10; NFKB2 |
Entrez GeneID | 4791; |
Swissprot | Q00653 |
WB Predicted band size | 120 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NFkB-p100. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from HT29 cells using NFkB-p100(Ab-866) Antibody P41251.
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Immunofluorescence staining of methanol-fixed Hela cells using NFkB-p100(Ab-866) Antibody P41251.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB-p100(Ab-866) Antibody P41251(left) or the same antibody preincubated with blocking peptide(right).