Rabbit Polyclonal Antibody to ATF2(Ab-62 or 44)
货号：
P41264
别名：
CREB2; CREBP1;
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P15336
规格：
目录价
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Description |
|---|
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. |
References |
|---|
| Sevilla A, et al. (2004) J Biol Chem. 279(26):27458-27465.Sakurai A, et al. (1991) Biochem Biophys Res Commun. 181(2): 629-635.Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089.Gupta S, et al. (1995) Science. 267: 389-393.Van Dam H, et al. (1995) EMBO J. 14(8): 1798-1811. |
Specification |
|
|---|---|
| Aliases | CREB2; CREBP1; |
| Entrez GeneID | 1386; |
| Swissprot | P15336 |
| WB Predicted band size | 65-75 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.serine 60~64 or 42~46 (N-D-S-V-I) derived from Human ATF2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from 293 and 3T3 cells using ATF2(Ab-62 or 44) Antibody P41264.
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Immunofluorescence staining of methanol-fixed Hela cells using ATF2(Ab-62 or 44) Antibody P41264.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ATF2(Ab-62 or 44) Antibody P41264(left) or the same antibody preincubated with blocking peptide(right).
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