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Rabbit Polyclonal Antibody to ATF2(Ab-62 or 44)
货号: P41264
别名: CREB2; CREBP1;
应用: WB,IHC,IF
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P15336
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Description

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.

References

Sevilla A, et al. (2004) J Biol Chem. 279(26):27458-27465.Sakurai A, et al. (1991) Biochem Biophys Res Commun. 181(2): 629-635.Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089.Gupta S, et al. (1995) Science. 267: 389-393.Van Dam H, et al. (1995) EMBO J. 14(8): 1798-1811.

Specification

Aliases CREB2; CREBP1;
Entrez GeneID 1386;
Swissprot P15336
WB Predicted band size 65-75 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa.serine 60~64 or 42~46 (N-D-S-V-I) derived from Human ATF2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200
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