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Mouse Monoclonal Antibody to FAP
货号: 31767
别名: FAPA; SIMP; DPPIV; FAPalpha
应用: IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q12884
规格:
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Description

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

References

1.Int J Mol Med. 2018 Jan;41(1):275-283.
2.Exp Mol Pathol. 2018 Feb;104(1):29-37.

Specification

Aliases FAPA; SIMP; DPPIV; FAPalpha
Entrez GeneID 2191
Swissprot Q12884
clone 5D9F6
WB Predicted band size 87.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human FAP (AA: extra 26-264) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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