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Rabbit Polyclonal Antibody to ICAM-1(Ab-512)
货号: P41327
别名: ICA1; ICAM1;
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P05362
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Description

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

References

Greenwood J, et al. (2003) J Immunol; 171(4):2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513(1-2):1-8. Chen YH, et al. (2001) J Cell Biochem; 82(3):512-521

Specification

Aliases ICA1; ICAM1;
Entrez GeneID 3383;
Swissprot P05362
WB Predicted band size 89-92kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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