Rabbit Polyclonal Antibody to IGF-1R(Ab-1161)
货号：
P41307
别名：
Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R;
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P08069
规格：
目录价
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Description |
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This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. |
References |
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| Li S, et al. (1994) J Biol Chem; 269(51). Hernandez-Sanchez C, et al. (1995) J Biol Chem. |
Specification |
|
|---|---|
| Aliases | Insulin-like growth factor I receptor; CD221; IGF1R; kinase IGF1R; |
| Entrez GeneID | 3480; |
| Swissprot | P08069 |
| WB Predicted band size | 200 95 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R . |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from 293 cells using IGF-1R(Ab-1161) Antibody P41307 and the same antibody preincubated with blocking peptide.
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Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R(Ab-1161) Antibody P41307.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R(Ab-1161) Antibody P41307(left) or the same antibody preincubated with blocking peptide(right).
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