Rabbit Polyclonal Antibody to cdc25C(Ab-216)
货号：
P41360
别名：
CDC25M1; MPIP3;
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P30307
规格：
目录价
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Description |
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cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded |
References |
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| protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348.Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860.Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677.Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995. |
Specification |
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|---|---|
| Aliases | CDC25M1; MPIP3; |
| Entrez GeneID | 995; |
| Swissprot | P30307 |
| WB Predicted band size | 60kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from HT29 cells using cdc25C(Ab-216) Antibody P41360 and the same antibody preincubated with blocking peptide.
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Immunofluorescence staining of methanol-fixed Hela cells using cdc25C(Ab-216) Antibody P41360.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using cdc25C(Ab-216) Antibody P41360(left) or the same antibody preincubated with blocking peptide(right).
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