Rabbit Polyclonal Antibody to DNA PKcs(Ab-2609)
货号：
P41388
别名：
DNPK1; PRKD; PRKDC; XRCC7; P460
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P78527
规格：
目录价
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Description |
|---|
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties |
References |
|---|
| Chan DW, et al. (2002) Genes Dev. Sep 15; 16(18): 2333-2338Ding Q, et al. (2003) Mol Cell Biol. Aug; 23(16): 5836-5848Douglas P, et al. (2002) Biochem J. Nov 15; 368(Pt 1): 243-251 |
Specification |
|
|---|---|
| Aliases | DNPK1; PRKD; PRKDC; XRCC7; P460 |
| Entrez GeneID | 5591; |
| Swissprot | P78527 |
| WB Predicted band size | 450kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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