产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Rabbit Polyclonal Antibody to DNA PKcs(Ab-2609)
货号: P41388
别名: DNPK1; PRKD; PRKDC; XRCC7; P460
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P78527
规格:
目录价
在线咨询

Description

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties

References

Chan DW, et al. (2002) Genes Dev. Sep 15; 16(18): 2333-2338Ding Q, et al. (2003) Mol Cell Biol. Aug; 23(16): 5836-5848Douglas P, et al. (2002) Biochem J. Nov 15; 368(Pt 1): 243-251

Specification

Aliases DNPK1; PRKD; PRKDC; XRCC7; P460
Entrez GeneID 5591;
Swissprot P78527
WB Predicted band size 450kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852