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Rabbit Polyclonal Antibody to MEK1(Ab-221)
货号: P41385
别名: ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q02750
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Description

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

References

Zebisch A, et al. (2006) Cancer Res; 66(7): 3401-8.Luciano BS, et al. (2006)J Biol Chem; 279(50): 52117-23.Wang X, et al. (2003) Oncogene; 22(1): 109-16.Gopalbhai K, et al. (2003) J Biol Chem; 278(10): 8118-25.Ling MT, et al. (2002)Oncogene; 21(55): 8498-505.

Specification

Aliases ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1
Entrez GeneID 5604;
Swissprot Q02750
WB Predicted band size 45kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around aa.219~223 (A-N-S-F-V) derived from Human MEK1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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