Rabbit Polyclonal Antibody to MEK1(Ab-221)
货号：
P41385
别名：
ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1
应用：
WB,IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q02750
规格：
目录价
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Description |
|---|
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |
References |
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| Zebisch A, et al. (2006) Cancer Res; 66(7): 3401-8.Luciano BS, et al. (2006)J Biol Chem; 279(50): 52117-23.Wang X, et al. (2003) Oncogene; 22(1): 109-16.Gopalbhai K, et al. (2003) J Biol Chem; 278(10): 8118-25.Ling MT, et al. (2002)Oncogene; 21(55): 8498-505. |
Specification |
|
|---|---|
| Aliases | ERK activator kinase 1; MAP kinase kinase 1; MAP2K1; MAPK/ERK kinase 1; MAPKK 1 |
| Entrez GeneID | 5604; |
| Swissprot | Q02750 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around aa.219~223 (A-N-S-F-V) derived from Human MEK1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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