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Rabbit Polyclonal Antibody to ASK1(Ab-83)
货号: P41342
别名: ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5
应用: WB,IHC,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q99683
规格:
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Description

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

References

Mabuchi S, et al. (2004) Endocrinology. 145(1): 49-58.Yuan ZQ, et al. (2003) J Biol Chem. 278(26): 23432-23440.Kim AH, et al. (2001) Mol Cell Biol. 21(3): 893-901.

Specification

Aliases ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5
Entrez GeneID 4217;
Swissprot Q99683
WB Predicted band size 155kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200
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