Rabbit Polyclonal Antibody to ASK1(Ab-83)
货号：
P41342
别名：
ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99683
规格：
目录价
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Description |
|---|
Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death. |
References |
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| Mabuchi S, et al. (2004) Endocrinology. 145(1): 49-58.Yuan ZQ, et al. (2003) J Biol Chem. 278(26): 23432-23440.Kim AH, et al. (2001) Mol Cell Biol. 21(3): 893-901. |
Specification |
|
|---|---|
| Aliases | ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5 |
| Entrez GeneID | 4217; |
| Swissprot | Q99683 |
| WB Predicted band size | 155kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from MDA-MB- 435 cells using ASK1(Ab-83) Antibody P41342 and the same antibody preincubated with blocking peptide.
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Immunofluorescence staining of methanol-fixed Hela cells using ASK1(Ab-83) Antibody P41342.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ASK1(Ab-83) Antibody P41342(left) or the same antibody preincubated with blocking peptide(right).
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