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Rabbit Polyclonal Antibody to Src(Ab-529)
货号: P41378
别名: C-SRC; SRC1;
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P12931
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Description

proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.

References

Pyper J.M., (1985) Mol. Cell. Biol. 5:831-838 Pyper J.M.(1990) Mol. Cell. Biol. 10:2035-2040 Xu W., (1997).Nature 385:595-602 Benes C.H., (2005) Cell 121:271-280

Specification

Aliases C-SRC; SRC1;
Entrez GeneID 6714;
Swissprot P12931
WB Predicted band size 60kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa. 527~531 (P-Q-Y-Q-P) derived from Human Src.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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