Rabbit Polyclonal Antibody to Src(Ab-529)
货号:
P41378
别名:
C-SRC; SRC1;
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P12931
规格:
目录价
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Description |
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proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. |
References |
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Pyper J.M., (1985) Mol. Cell. Biol. 5:831-838 Pyper J.M.(1990) Mol. Cell. Biol. 10:2035-2040 Xu W., (1997).Nature 385:595-602 Benes C.H., (2005) Cell 121:271-280 |
Specification |
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Aliases | C-SRC; SRC1; |
Entrez GeneID | 6714; |
Swissprot | P12931 |
WB Predicted band size | 60kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around aa. 527~531 (P-Q-Y-Q-P) derived from Human Src. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HT29, Hela and MDA cells using Src(Ab-529) Antibody P41378.
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Western Blot analysis of Hela /293 cells using Src Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Src(Ab-529) Antibody P41378(left) or the same antibody preincubated with blocking peptide(right).