Rabbit Polyclonal Antibody to p27Kip1(Ab-10)
货号:
P41364
别名:
CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
P46527
规格:
目录价
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Description |
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Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events. |
References |
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Le XF, et al. (2003)J Biol Chem. Connor MK, et al. (2003)Mol Biol Cell; 14(1): 201-13. McAllister SS, et al. (2003) Mol Cell Biol; 23(1): 216-28. Chopra S, et al. (2002)J Biol Chem; 277(36): 32413-6. Boehm M, et al. (2002)EMBO J; 21(13): 3390-401. |
Specification |
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Aliases | CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1 |
Entrez GeneID | 1027; |
Swissprot | P46527 |
WB Predicted band size | 27kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around aa.8~12 (N-G-S-P-S) derived from Human p27Kip1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |