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Rabbit Polyclonal Antibody to p27Kip1(Ab-10)
货号: P41364
别名: CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P46527
规格:
目录价
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Description

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

References

Le XF, et al. (2003)J Biol Chem. Connor MK, et al. (2003)Mol Biol Cell; 14(1): 201-13. McAllister SS, et al. (2003) Mol Cell Biol; 23(1): 216-28. Chopra S, et al. (2002)J Biol Chem; 277(36): 32413-6. Boehm M, et al. (2002)EMBO J; 21(13): 3390-401.

Specification

Aliases CDKN1B; CDN1B; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; KIP1
Entrez GeneID 1027;
Swissprot P46527
WB Predicted band size 27kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa.8~12 (N-G-S-P-S) derived from Human p27Kip1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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