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Rabbit Polyclonal Antibody to p21Cip1(Ab-145)
货号: P41363
别名: CAP20; CDK-interacting protein 1; CDKN1; CDKN1A; CDN1A
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P38936
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Description

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.

References

Ocker M Int,et al. (2007)J Biochem Cell Biol. 39(7-8):1367-74.Dangi S, et al.(2006)Cell Prolif. 39(4):261-79.Chen J,et al.(2006)Am J Physiol Heart Circ Physiol. 290(4):H1575-86

Specification

Aliases CAP20; CDK-interacting protein 1; CDKN1; CDKN1A; CDN1A
Entrez GeneID 1026;
Swissprot P38936
WB Predicted band size 21kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.143~147 (R-Q-T-S-M) derived from Human p21Cip1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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