Rabbit Polyclonal Antibody to p21Cip1(Ab-145)
货号：
P41363
别名：
CAP20; CDK-interacting protein 1; CDKN1; CDKN1A; CDN1A
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P38936
规格：
目录价
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Description |
|---|
May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. |
References |
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| Ocker M Int,et al. (2007)J Biochem Cell Biol. 39(7-8):1367-74.Dangi S, et al.(2006)Cell Prolif. 39(4):261-79.Chen J,et al.(2006)Am J Physiol Heart Circ Physiol. 290(4):H1575-86 |
Specification |
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|---|---|
| Aliases | CAP20; CDK-interacting protein 1; CDKN1; CDKN1A; CDN1A |
| Entrez GeneID | 1026; |
| Swissprot | P38936 |
| WB Predicted band size | 21kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.143~147 (R-Q-T-S-M) derived from Human p21Cip1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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