Rabbit Polyclonal Antibody to AFX(Ab-197)
货号：
P41373
别名：
AFX; FOXO4; AFX1; Afxh;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P98177
规格：
目录价
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Description |
|---|
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. |
References |
|---|
| Di Maira G, et al. (2005)Cell Death Differ; 12(6): 668-77.Essers MA, et al. EMBO J 2004 Nov. 11.Brownawell AM, (2001) Mol Cell Biol; 21(10): 3534-46.Kops GJ, et al. (1999) Nature; 398(6728): 630-4. |
Specification |
|
|---|---|
| Aliases | AFX; FOXO4; AFX1; Afxh; |
| Entrez GeneID | 4303; |
| Swissprot | P98177 |
| WB Predicted band size | 65kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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