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Rabbit Polyclonal Antibody to AFX(Ab-197)
货号: P41373
别名: AFX; FOXO4; AFX1; Afxh;
应用: WB,IHC
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P98177
规格:
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Description

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

References

Di Maira G, et al. (2005)Cell Death Differ; 12(6): 668-77.Essers MA, et al. EMBO J 2004 Nov. 11.Brownawell AM, (2001) Mol Cell Biol; 21(10): 3534-46.Kops GJ, et al. (1999) Nature; 398(6728): 630-4.

Specification

Aliases AFX; FOXO4; AFX1; Afxh;
Entrez GeneID 4303;
Swissprot P98177
WB Predicted band size 65kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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