Rabbit Polyclonal Antibody to MEK1/MEK2(Ab-217/221)
货号：
P41407
别名：
ERK activator kinase 1/ERK activator kinase2; MAP kinase kinase 1/MAP kinase kinase 2; MAP2K1/MAP2K1; MAPK/ERK kinase 1/MAPK/ERK kinase 2; MAPKK 1/MAPKK 1
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q02750
规格：
目录价
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Description |
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Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |
References |
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| Shen R, et al. (2002) Mol Cell Biol; 22(10): 3230-3236Preisinger C, et al. (2005) EMBO J; 24(4): 753-765Laine P, et al. (2000) Biochem J; 349(Pt 1): 19-25Yaglom J, et al. (2003) Mol Cell Biol; 23(11): 3813-3824Dahan S, et al. (2002) Infect Immun; 70(5): 2304-2310 |
Specification |
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|---|---|
| Aliases | ERK activator kinase 1/ERK activator kinase2; MAP kinase kinase 1/MAP kinase kinase 2; MAP2K1/MAP2K1; MAPK/ERK kinase 1/MAPK/ERK kinase 2; MAPKK 1/MAPKK 1 |
| Entrez GeneID | 5604; |
| Swissprot | Q02750 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.215~219/219~223 (I-D-S-M-A) derived from Human MEK1/MEK2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from 293 cells using MEK1/MEK2(Ab-217/221) Antibody P41407 and the same antibody preincubated with blocking peptide.
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Immunofluorescence staining of methanol-fixed Hela cells using MEK1/MEK2(Ab-217/221) Antibody P41407.
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using MEK1/MEK2(Ab-217/221) Antibody P41407(left) or the same antibody preincubated with blocking peptide(right).
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