Rabbit Polyclonal Antibody to Raf1(Ab-338)
货号：
P41406
别名：
C-RAF; C-Raf; CRAF
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P04049
规格：
目录价
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Description |
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Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3. |
References |
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| Adams DG,et al. (2005)J Biol Chem. 280(52):42644-54.Miura S, et al. (2003) Biochem Biophys Res Commun. 306(4):924-9.Noser JA,et al.(2007)Mol Ther.15(8):1531-6. |
Specification |
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|---|---|
| Aliases | C-RAF; C-Raf; CRAF |
| Entrez GeneID | 5894; |
| Swissprot | P04049 |
| WB Predicted band size | 73kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.336~340 (R-D-S-S-Y) derived from Human RAF. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from 293 cells using Raf1(Ab-338) Antibody P41406 and the same antibody preincubated with blocking peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1(Ab-338) Antibody P41406(left) or the same antibody preincubated with blocking peptide(right).
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