Rabbit Polyclonal Antibody to IRS-1(Ab-636)
货号：
P41426
别名：
IRS-1; IRS1;
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P35568
规格：
目录价
在线咨询
Description |
|---|
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
References |
|---|
| Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645Tzatsos A, et al. (2006) Mol Cell Biol; 26(1): 63-76Kadowaki T, et al. (2000) J Clin Invest; 106(4): 459-465Ozes ON, et al. (2001) Proc Natl Acad Sci U S A; 98(8): 4640-4645Szanto I, et al. (2000) Proc Natl Acad Sci U S A; 97(5): 2355-2360 |
Specification |
|
|---|---|
| Aliases | IRS-1; IRS1; |
| Entrez GeneID | 3667; |
| Swissprot | P35568 |
| WB Predicted band size | 180kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa.634~638 (P-M-S-P-K) derived from Human IRS-1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
-
Western blot analysis of extracts from 293 cells using IRS-1(Ab-636) Antibody P41426.
-
Immunofluorescence staining of methanol-fixed Hela cells using IRS-1(Ab-636) Antibody P41426.
-
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IRS-1(Ab-636) Antibody P41426(left) or the same antibody preincubated with blocking peptide(right).
鄂公网安备42018502007531号
