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Rabbit Polyclonal Antibody to p56Dok-2(Ab-299)
货号: P41463
别名: DOK2
应用: WB,IHC,IF
反应种属: Human
抗体类型: Primary antibody
Swissprot: O60496
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Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

References

Feng Cong, et,al. (1999) Mol. Cell. Biol; 19: 8314 - 8325.Serge Lemay, et,al. (2000) Mol. Cell. Biol; 20: 2743 - 2754.Ute Schaeper, et,al.(2000) J. Cell Biol; 149: 1419.Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151.

Specification

Aliases DOK2
Entrez GeneID 9046;
Swissprot O60496
WB Predicted band size 56kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IHC 1/50-1/100
IF 1/100-1/200
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