Rabbit Polyclonal Antibody to p56Dok-2(Ab-299)
货号：
P41463
别名：
DOK2
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O60496
规格：
目录价
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Description |
|---|
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation |
References |
|---|
| Feng Cong, et,al. (1999) Mol. Cell. Biol; 19: 8314 - 8325.Serge Lemay, et,al. (2000) Mol. Cell. Biol; 20: 2743 - 2754.Ute Schaeper, et,al.(2000) J. Cell Biol; 149: 1419.Miyuki Honma, et,al. (2006) Genes Cells; 11: 143 - 151. |
Specification |
|
|---|---|
| Aliases | DOK2 |
| Entrez GeneID | 9046; |
| Swissprot | O60496 |
| WB Predicted band size | 56kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from JK cells using p56Dok-2(Ab-299) Antibody P41463.
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Immunofluorescence staining of methanol-fixed Hela cells using p56Dok-2(Ab-299) Antibody P41463.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p56Dok-2(Ab-299) Antibody P41463(left) or the same antibody preincubated with blocking peptide(right).
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