Rabbit Polyclonal Antibody to p62Dok(Ab-398)
货号:
P41462
别名:
DOK1
应用:
WB,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q99704
规格:
目录价
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Description |
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DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
References |
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Michael J. Wick,et,al. (2001) J. Biol. Chem; 276: 42843 - 42850.Paul D. Simoncic, et,al. (2006) Mol. Cell. Biol; 26: 4149 - 4160.Nadia Dub |
Specification |
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Aliases | DOK1 |
Entrez GeneID | 1796; |
Swissprot | Q99704 |
WB Predicted band size | 62kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around aa.396~400 (P-I-Y-D-E) derived from Human p62Dok. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from K562, HL-60 and JK cells using p62Dok(Ab-398) Antibody P41462.
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Immunofluorescence staining of methanol-fixed Hela cells using p62Dok(Ab-398) Antibody P41462.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p62Dok(Ab-398) Antibody P41462(left) or the same antibody preincubated with blocking peptide(right).