Rabbit Polyclonal Antibody to PKCd(Ab-645)
货号：
P41479
别名：
nPKC-delta
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q05655
规格：
目录价
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Description |
|---|
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin. |
References |
|---|
| Kei Sakamoto, et,al. (2003) Am J Physiol Endocrinol Metab, ; 285: E1081 - E1088. Ling Zhang, et,al. (2004) J. Biol. Chem ; 279: 28315 - 28319. Kristof Van Kolen et,al. (2006) FEBS J ; 273: 1843 - 1854. Martin Villalba, et,al. (2002) J. Cell Biol ; 157: 253. |
Specification |
|
|---|---|
| Aliases | nPKC-delta |
| Entrez GeneID | 5580; |
| Swissprot | Q05655 |
| WB Predicted band size | 78kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa. 643~647 (R-L-S-Y-S) derived from Human PKCd. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from PC12 cells using PKCd(Ab-645) Antibody P41479.
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Immunofluorescence staining of methanol-fixed Hela cells using PKCd(Ab-645) Antibody P41479.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PKCd(Ab-645) Antibody P41479(left) or the same antibody preincubated with blocking peptide(right).
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