Rabbit Polyclonal Antibody to p7S6 Kinase
货号：
P41456
别名：
KS6B1; P70-S6K; RPS6KB1; S6K;
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P23443
规格：
目录价
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Description |
|---|
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation. |
References |
|---|
| Satoru Eguchi et al. (1999) J Biol Chem, Vol. 274: 36843-36851 Papst PJ, et al. (1998) J Biol Chem. 273(24):15077-84. Ulrike Krause et al. (2002) Eur. J. Biochem. 269: 3751-3759 c Le, X.F, et al. (2003) Oncogene 22: 484 |
Specification |
|
|---|---|
| Aliases | KS6B1; P70-S6K; RPS6KB1; S6K; |
| Entrez GeneID | 6198; |
| Swissprot | P23443 |
| WB Predicted band size | 70 85 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa. 409~413 (I-R-S-P-R) derived from Human p70 S6 Kinase. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of extracts from 293 cells using p70 S6 Kinase(Ab-411) Antibody P41456.
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Immunofluorescence staining of methanol-fixed MCF7 cells using p70 S6 Kinase(Ab-411) Antibody P41456.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase(Ab-411) Antibody P41456(left) or the same antibody preincubated with blocking peptide(right).
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