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Rabbit Polyclonal Antibody to Melanoma-associated antigen D1
货号: P41517
别名: MAGED1
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9QYH6
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Description

Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

References

Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20. Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31. Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.

Specification

Aliases MAGED1
Entrez GeneID 94275;
Swissprot Q9QYH6
WB Predicted band size 95kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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