Rabbit Polyclonal Antibody to PKCz(Ab-410)
货号：
P41497
别名：
PKC2; PKC-ZETA; PRKCZ
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q05513
规格：
目录价
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Description |
|---|
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization. |
References |
|---|
| Parmentier JH, et al. (2004) BMC Cell Biol; 5: 4.Castrillo A, et al. (2003) Mol Cell Biol; 23(4): 1196-1208.Paramio JM, et al. ( 2001) Mol Cell Biol; 21(21): 7449-7459.Braiman L, et al. (2001) Mol Cell Biol; 21(22): 7852-7861. |
Specification |
|
|---|---|
| Aliases | PKC2; PKC-ZETA; PRKCZ |
| Entrez GeneID | 5590; |
| Swissprot | Q05513 |
| WB Predicted band size | 78kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around aa. 408~412 ( T-S-T-F-C) derived from PKCz |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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