Rabbit Polyclonal Antibody to CRY1
货号:
P41522
别名:
PHLL1
应用:
WB
反应种属:
Mouse
抗体类型:
Primary antibody
Swissprot:
Q16526
规格:
目录价
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Description |
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Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL |
References |
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Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45. Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8. Stratmann M,et al.(2010) Genes Dev.24(12):1317-28. |
Specification |
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Aliases | PHLL1 |
Entrez GeneID | 1407; |
Swissprot | Q16526 |
WB Predicted band size | 60kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Mouse |
Immunogen | Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |