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Rabbit Polyclonal Antibody to CRY1
货号: P41522
别名: PHLL1
应用: WB
反应种属: Mouse
抗体类型: Primary antibody
Swissprot: Q16526
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Description

Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL

References

Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45. Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8. Stratmann M,et al.(2010) Genes Dev.24(12):1317-28.

Specification

Aliases PHLL1
Entrez GeneID 1407;
Swissprot Q16526
WB Predicted band size 60kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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