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Rabbit Polyclonal Antibody to a-catenin(Ab-641)
货号: P41510
别名: Cadherin-associated protein; Alpha E-catenin; NY-REN-13 antigen
应用: WB
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: P35221
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Description

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.

References

Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765Drees, F. et al. (2005) Cell 123, 903-915.Yamada, S. et al. (2005) Cell 123, 889-901.Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.

Specification

Aliases Cadherin-associated protein; Alpha E-catenin; NY-REN-13 antigen
Entrez GeneID 1495;
Swissprot P35221
WB Predicted band size 100kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around aa. 639~643 (D-D-S-D-F) derived from Human a-catenin.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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