Rabbit Polyclonal Antibody to Caspase 9
货号：
P41524
别名：
ICE-like apoptotic protease 6
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P55211
规格：
目录价
在线咨询
Description |
|---|
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
References |
|---|
| Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556.Deveraux, Q. L. et al. (1998) EMBO J. 17, 2215-2223.Li, P. et al. (1997) Cell 91, 479-489. |
Specification |
|
|---|---|
| Aliases | ICE-like apoptotic protease 6 |
| Entrez GeneID | 842; |
| Swissprot | P55211 |
| WB Predicted band size | 47 37 35kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
鄂公网安备42018502007531号
