Rabbit Polyclonal Antibody to ABL1/2 (Ab-393/439)
货号：
P41554
别名：
ABL; v-abl; c-ABL; p150; JTK7
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P00519
规格：
目录价
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Description |
|---|
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
References |
|---|
| Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259. |
Specification |
|
|---|---|
| Aliases | ABL; v-abl; c-ABL; p150; JTK7 |
| Entrez GeneID | 25; |
| Swissprot | P00519 |
| WB Predicted band size | 135 210kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around aa.391~395/437~441(D-T-Y-T-A) derived from Human ABL1/2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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