Rabbit Polyclonal Antibody to Twist2
货号:
P41589
别名:
DERMO1; MGC117334; bHLHa39
应用:
WB,IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q8WVJ9
规格:
目录价
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Description |
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Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. |
References |
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Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000) |
Specification |
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Aliases | DERMO1; MGC117334; bHLHa39 |
Entrez GeneID | 117581; |
Swissprot | Q8WVJ9 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/100-1/500 |
IHC | 1/100-1/500 |