Rabbit Polyclonal Antibody to DLC1 (Ab-868)
货号：
P41603
别名：
ARHGAP7; KIAA1723; STARD12
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96QB1
规格：
目录价
在线咨询
Description |
|---|
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. |
References |
|---|
| 1)protein DLC-1 on cell morphology and migration."Kim T.Y., Healy K.D., Der C.J., Sciaky N., Bang Y.J., Juliano R.L.J. Biol. Chem. 283:32762-32770(2008) 2)Kawai K., Iwamae Y., Yamaga M., Kiyota M., Ishii H., Hirata H., Homma Y., Yagisawa H.Genes Cells 14:227-241(2009) 3)Erlmann P., Schmid S., Horenkamp F.A., Geyer M., Pomorski T.G., Olayioye M.A.Mol. Biol. Cell 20:4400-4411(2009) |
Specification |
|
|---|---|
| Aliases | ARHGAP7; KIAA1723; STARD12 |
| Entrez GeneID | 10395; |
| Swissprot | Q96QB1 |
| WB Predicted band size | 171, 127, 123, 114kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around aa.866~870 (R-N-S-S-S) derived from Human DLC1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
鄂公网安备42018502007531号
