Rabbit Polyclonal Antibody to ABCB8
货号:
P41613
别名:
ATP-binding cassette sub-family B member 8, MABC1, M-ABC1, EST328128
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q9NUT2
规格:
目录价
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Description |
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes. |
Specification |
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Aliases | ATP-binding cassette sub-family B member 8, MABC1, M-ABC1, EST328128 |
Entrez GeneID | 11194; |
Swissprot | Q9NUT2 |
WB Predicted band size | 76kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein corresponding to a region derived from 394-693 amino acids of Human ATP-binding cassette sub-family B member 8 |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
ELISA | 1:2000-1:5000 |
Product Image
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Gel: 8%SDS-PAGELane1: Hela cell lysate Lane2: HepG2 cell lysateLysates: 20 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilutionExposure time: 1 minute
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The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 31025(ABCB8 Antibody) at dilution 1/17, on the right is treated with the fusion protein.