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Rabbit Polyclonal Antibody to GIT1 (Ab-383)
货号: P41610
别名: ARF;GAP;CAT-1;CAT1
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9Y2X7
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Description

GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes.

References

Manabe R., Kovalenko M., Webb D.J., Horwitz A.R.J. Cell Sci. 115:1497-1510(2002)

Specification

Aliases ARF;GAP;CAT-1;CAT1
Entrez GeneID 28964;
Swissprot Q9Y2X7
WB Predicted band size 84kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Peptide sequence around aa.381~385 (H-D-Y-D-S) derived from Human GIT1 .
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
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