Rabbit Polyclonal Antibody to GIT1 (Ab-383)
货号:
P41610
别名:
ARF;GAP;CAT-1;CAT1
应用:
WB
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9Y2X7
规格:
目录价
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Description |
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GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. |
References |
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Manabe R., Kovalenko M., Webb D.J., Horwitz A.R.J. Cell Sci. 115:1497-1510(2002) |
Specification |
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Aliases | ARF;GAP;CAT-1;CAT1 |
Entrez GeneID | 28964; |
Swissprot | Q9Y2X7 |
WB Predicted band size | 84kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around aa.381~385 (H-D-Y-D-S) derived from Human GIT1 . |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/1000 |