Rabbit Polyclonal Antibody to Bax (Ab-167)
货号：
P41656
别名：
Apoptosis regulator BAX; membrane isoform alpha; BAXA; Bcl2-associated X protein;
应用：
WB,IF
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q07812
规格：
目录价
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Description |
|---|
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.Oltvai Z.N., Cell 74:609-619(1993).Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).Guo B., Nature 423:456-461(2003) |
Specification |
|
|---|---|
| Aliases | Apoptosis regulator BAX; membrane isoform alpha; BAXA; Bcl2-associated X protein; |
| Entrez GeneID | 581; |
| Swissprot | Q07812 |
| WB Predicted band size | 21kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized non-phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IF | 1/100-1/500 |
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