Rabbit Polyclonal Antibody to Nuclear Receptor NR4A1 (Ab-351)
货号：
P41685
别名：
Early response protein NAK1; GFRP; GFRP1; HMR; N10
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P22736
规格：
目录价
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Description |
|---|
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.Nakai A., Mol. Endocrinol. 4:1438-1443(1990).Chang C., J. Steroid Biochem. 34:391-395(1989).The MGC Project Team; Genome Res. 14:2121-2127(2004). |
Specification |
|
|---|---|
| Aliases | Early response protein NAK1; GFRP; GFRP1; HMR; N10 |
| Entrez GeneID | 3164; |
| Swissprot | P22736 |
| WB Predicted band size | 60kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from COS-7 cells, using Nuclear Receptor NR4A1 (Ab-351) antibody P41685.
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Western blot analysis of extracts from HepG2 cells (Lane 2), using Nuclear Receptor NR4A1 (Ab-351) antiobdy P41685. The lane on the left is treated with synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Nuclear Receptor NR4A1 (Ab-351) antibody P41685.
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