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Rabbit Polyclonal Antibody to CREB (Ab-129/133)
货号: P41689
别名: cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1;
应用: WB,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: P16220
规格:
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Description

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55.Tan Y, et al.( 1996) EMBO J; 15(17): 4629-42.Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385.Mayo LD, et al. (2001) Biol Chem; 276(27): 25184-9.Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-59

Specification

Aliases cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1;
Entrez GeneID 1385;
Swissprot P16220
WB Predicted band size 43kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 or serine 133(S-R-R-P-S).
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
IHC 1/50-1/100
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