Rabbit Polyclonal Antibody to CREB (Ab-129/133)
货号:
P41689
别名:
cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1;
应用:
WB,IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P16220
规格:
目录价
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Description |
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Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55.Tan Y, et al.( 1996) EMBO J; 15(17): 4629-42.Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385.Mayo LD, et al. (2001) Biol Chem; 276(27): 25184-9.Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-59 |
Specification |
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Aliases | cAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1; |
Entrez GeneID | 1385; |
Swissprot | P16220 |
WB Predicted band size | 43kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized non-phosphopeptide derived from human CREB around the phosphorylation site of serine 129 or serine 133(S-R-R-P-S). |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |