Rabbit Polyclonal Antibody to ILK (Ab-246)
货号：
P41709
别名：
59 kDa serine/threonine protein kinase; EC 2.7.11.1; ILK-1; ILK1; Integrin-linked protein kinase
应用：
WB,IHC
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
Q13418
规格：
目录价
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Description |
|---|
Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.Hannigan G.E.,Nature 379:91-96(1996).Janji B.,Oncogene 19:3069-3077(2000).Tadic B.,Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. |
Specification |
|
|---|---|
| Aliases | 59 kDa serine/threonine protein kinase; EC 2.7.11.1; ILK-1; ILK1; Integrin-linked protein kinase |
| Entrez GeneID | 3611; |
| Swissprot | Q13418 |
| WB Predicted band size | 42kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | Synthesized non-phosphopeptide derived from human ILK around the phosphorylation site of serine 246 (I-F-S(p)-H-P). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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