Rabbit Polyclonal Antibody to TTK (Ab-676)
货号：
P41729
别名：
dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P33981
规格：
目录价
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Description |
|---|
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.Mills G.B., J. Biol. Chem. 267:16000-16006(1992).Ota T., Nat. Genet. 36:40-45(2004).Mungall A.J., Nature 425:805-811(2003) |
Specification |
|
|---|---|
| Aliases | dual specificity protein kinase TTK; EC 2.7.12.1; Esk1; Mps1; MPS1L1 |
| Entrez GeneID | 7272; |
| Swissprot | P33981 |
| WB Predicted band size | 100kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human TTK around the phosphorylation site of threonine 676 (D-T-T(p)-S-V). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody P41729.
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Western blot analysis of extracts from colo cells (Lane 2), using TTK (Ab-676) antiobdy P41729. The lane on the left is treated with synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody P41729.
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