Rabbit Polyclonal Antibody to B-RAF (Ab-446)
货号：
P41706
别名：
B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P15056
规格：
目录价
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Description |
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Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003) |
Specification |
|
|---|---|
| Aliases | B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1 |
| Entrez GeneID | 673; |
| Swissprot | P15056 |
| WB Predicted band size | 84kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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