Rabbit Polyclonal Antibody to Mnk1 (Ab-385)
货号：
P41758
别名：
EC 2.7.11.1; kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9BUB5
规格：
目录价
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Description |
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May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.Fukunaga R., EMBO J. 16:1921-1933(1997).Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).O'Loghlen A., Exp. Cell Res. 299:343-355(2004). |
Specification |
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|---|---|
| Aliases | EC 2.7.11.1; kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1 |
| Entrez GeneID | 8569; |
| Swissprot | Q9BUB5 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized non-phosphopeptide derived from human Mnk1 around the phosphorylation site of threonine 385 (L-P-T(p)-P-Q). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
Product Image
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Western blot analysis of extracts from 3T3 cells, treated with PMA (125ng/ml, 30mins), using Mnk1 (Ab-385) antibody P41758.
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Western blot analysis of extracts from HepG2 cells (Lane 2), K562 cells (Lane 3) and Jurket cells (Lane 4), using Mnk1 (Ab-385) antiobdy P41758. The lane on the left is treated with systhesized peptide.
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