Rabbit Polyclonal Antibody to GAB2 (Ab-159)
货号：
P41736
别名：
GABJ; GRB2-associated binding protein 2; KIAA0571; pp100;
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UQC2
规格：
目录价
在线咨询
Description |
|---|
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis |
References |
|---|
| Nishida K., Blood 93:1809-1816(1999) Nagase T., DNA Res. 5:31-39(1998) Taylor T.D., Nature 440:497-500(2006). |
Specification |
|
|---|---|
| Aliases | GABJ; GRB2-associated binding protein 2; KIAA0571; pp100; |
| Entrez GeneID | 9846; |
| Swissprot | Q9UQC2 |
| WB Predicted band size | 97kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human GAB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
-
Western blot analysis of extracts from COS cells, using GAB2 (Ab-159) antibody P41736.
-
Western blot analysis of extracts from 293 cells (Lane 2), using GAB2 (Ab-159) antiobdy P41736. The lane on the left is treated with synthesized peptide.
-
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GAB2 (Ab-159) antibody P41736.
鄂公网安备42018502007531号
