Rabbit Polyclonal Antibody to Epo-R (Ab-426)
货号：
P41782
别名：
Erythropoietin receptor; EPO-R;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P19235
规格：
目录价
在线咨询
Description |
|---|
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.Winkelmann J.C., Blood 76:24-30(1990) [PubMed: 2163695].Jones S.S.,Blood 76:31-35(1990) [PubMed: 2163696].Noguchi C.T., Blood 78:2548-2556(1991) [PubMed: 1668606]. |
Specification |
|
|---|---|
| Aliases | Erythropoietin receptor; EPO-R; |
| Entrez GeneID | 2057; |
| Swissprot | P19235 |
| WB Predicted band size | 55kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from Internal of human Epo-R. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
鄂公网安备42018502007531号
