Rabbit Polyclonal Antibody to TPH2 (Ab-19)
货号：
P41775
别名：
Neuronal tryptophan hydroxylase; NTPH; Tryptophan 5- monooxygenase 2;
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q8IWU9
规格：
目录价
在线咨询
Description |
|---|
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.Bader M., Science 299:76-76(2003).Gibbs R.A., Nature 440:346-351(2006).Pandey A., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007). |
Specification |
|
|---|---|
| Aliases | Neuronal tryptophan hydroxylase; NTPH; Tryptophan 5- monooxygenase 2; |
| Entrez GeneID | 121278; |
| Swissprot | Q8IWU9 |
| WB Predicted band size | 56kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized non-phosphopeptide derived from human TPH2 around the phosphorylation site of serine 19 (G-FI-S(p)-L-D). |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
鄂公网安备42018502007531号
