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Rabbit Polyclonal Antibody to Claudin 1
货号: P41790
别名: Claudin-10; OSP-like protein; CLDN10;
应用: WB
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: P78369
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Description

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney.Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 - 556.Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 - 944.Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 - F1299.Anne Florin, Endocrinology, Mar 2005; 146: 153

Specification

Aliases Claudin-10; OSP-like protein; CLDN10;
Entrez GeneID 9071;
Swissprot P78369
WB Predicted band size 25kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized peptide derived from human Claudin 10.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/3000
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