Rabbit Polyclonal Antibody to GRK2 (Ab-86)
货号:
P41771
别名:
ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1
应用:
WB
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
P25098
规格:
目录价
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Description |
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Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.Benovic J.L., FEBS Lett. 283:122-126(1991).Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).Penn R.B., J. Biol. Chem. 269:14924-14930(1994). |
Specification |
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Aliases | ADRBK1; adrenergic; beta; receptor kinase 1; ARBK1 |
Entrez GeneID | 156; |
Swissprot | P25098 |
WB Predicted band size | 80kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from N-terminal of human ADRBK1. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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WB | 1/500-1/3000 |