Rabbit Polyclonal Antibody to FADD (Ab-191)
货号：
P41769
别名：
FADD; Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q61160
规格：
目录价
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Description |
|---|
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity.Zhang J., Mol. Cell. Biol. 16:2756-2763(1996).Hsu H., Cell 84:299-308(1996).Carninci P., Science 309:1559-1563(2005) |
Specification |
|
|---|---|
| Aliases | FADD; Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain |
| Entrez GeneID | 14082; |
| Swissprot | Q61160 |
| WB Predicted band size | 30kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from C-terminal of human FADD. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
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