Rabbit Polyclonal Antibody to E2F4
货号：
P41798
别名：
E2F-4; p107/p130-binding protein;
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q16254
规格：
目录价
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Description |
|---|
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1.Kathryn M. Kinross, Blood, Aug 2006; 108: 886 - 895.Dawei Wang, Mol. Cell. Biol., May 2000; 20: 3417 - 3424.Stephan P. Persengiev, Mol. Cell. Biol., Sep 1999; 19: 6048 - 6056.Stefan Gaubatz, Mol. Cell. Biol., Feb 2001; 21: 1384 - 1392. |
Specification |
|
|---|---|
| Aliases | E2F-4; p107/p130-binding protein; |
| Entrez GeneID | 1874; |
| Swissprot | Q16254 |
| WB Predicted band size | 44kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human E2F4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of extracts from COS7 cells, using E2F4 antibody P41798.
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Western blot analysis of extracts from JK cells (Lane 2), using E2F4 antiobdy P41798. The lane on the left is treated with synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using E2F4 antibody P41798.
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