Rabbit Polyclonal Antibody to CREB-BP
货号：
P41793
别名：
CREB-binding protein; CBP CBP/MOZ FUSION GENE;
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q92793
规格：
目录价
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Description |
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Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.Zoi Lygerou, Nucleic Acids Res., Feb 1994; 22: 5332 - 5340.Karsten Grote, J. Biol. Chem., Dec 2004; 279: 55675 - 55681.Kumi Nagamoto-Combs, J. Biol. Chem., Feb 1997; 272: 6051.Stephen J. Elliman, Isaac, J. Biol. Chem., Jan 2006; 281: 16 -19 |
Specification |
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|---|---|
| Aliases | CREB-binding protein; CBP CBP/MOZ FUSION GENE; |
| Entrez GeneID | 1387; |
| Swissprot | Q92793 |
| WB Predicted band size | 265kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from human CREB-BP. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/500 |
Product Image
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Western blot analysis of extracts from HeLa cells, treated with insulin (0.01U/ml, 15mins), using CREB-BP antibody P41793.
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Immunofluorescence analysis of A549 cells, using CREB-BP antibody P41793.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB-BP antibody P41793.
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