Rabbit Polyclonal Antibody to Sodium Channel-pan
货号：
P41835
别名：
CIN5; HH1; SCN5A; Sodium channel protein; cardiac muscle alpha-subunit
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q14524
规格：
目录价
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Description |
|---|
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na+ channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.Sebastian K.G. Maier, Circulation, Mar 2004; 109: 1421 - 1427. T.R. Cummins, Neurology, Jan 2003; 60: 224 - 229. Christopher A. Ahern, Circ. Res., May 2005; 96: 991 - 998. Jyoti Dhar Malhotra, Circulation, Mar 2001; 103: 1303 - 1310. |
Specification |
|
|---|---|
| Aliases | CIN5; HH1; SCN5A; Sodium channel protein; cardiac muscle alpha-subunit |
| Entrez GeneID | 6331; |
| Swissprot | Q14524 |
| WB Predicted band size | 230kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from human sodium channel. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
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